Source code for pyhealth.models.sequence.stagenet

# -*- coding: utf-8 -*-

"""StageNet model. Adapted and modified from

https://github.com/v1xerunt/StageNet

"""
import os
import math
import torch
import torch.nn as nn
from torch.autograd import Variable
from torch.nn import Parameter
from torch import Tensor
import pickle
import warnings
from ._loss import callLoss
from ._dlbase import BaseControler

warnings.filterwarnings('ignore')

[docs]class callPredictor(nn.Module): def __init__(self, input_dim = None, hidden_dim = 384, conv_size = 10, levels = 3, dropconnect = 0.3, dropout = 0.3, dropres = 0.3, label_size = None, device = None ): super(callPredictor, self).__init__() assert hidden_dim % levels == 0 self.dropout = dropout self.dropconnect = dropconnect self.dropres = dropres self.input_dim = input_dim self.hidden_dim = hidden_dim self.conv_dim = hidden_dim self.conv_size = conv_size self.output_dim = label_size self.levels = levels self.chunk_size = hidden_dim // levels self.device = device self.kernel = nn.Linear(int(input_dim+1), int(hidden_dim*4+levels*2)) nn.init.xavier_uniform_(self.kernel.weight) nn.init.zeros_(self.kernel.bias) self.recurrent_kernel = nn.Linear(int(hidden_dim+1), int(hidden_dim*4+levels*2)) nn.init.orthogonal_(self.recurrent_kernel.weight) nn.init.zeros_(self.recurrent_kernel.bias) self.nn_scale = nn.Linear(int(hidden_dim), int(hidden_dim // 6)) self.nn_rescale = nn.Linear(int(hidden_dim // 6), int(hidden_dim)) self.nn_conv = nn.Conv1d(int(hidden_dim), int(self.conv_dim), int(conv_size), 1) self.nn_output = nn.Linear(int(self.conv_dim), int(self.output_dim)) if self.dropconnect: self.nn_dropconnect = nn.Dropout(p=dropconnect) self.nn_dropconnect_r = nn.Dropout(p=dropconnect) if self.dropout: self.nn_dropout = nn.Dropout(p=dropout) self.nn_dropres = nn.Dropout(p=dropres)
[docs] def cumax(self, x, mode='l2r'): if mode == 'l2r': x = torch.softmax(x, dim=-1) x = torch.cumsum(x, dim=-1) return x elif mode == 'r2l': x = torch.flip(x, [-1]) x = torch.softmax(x, dim=-1) x = torch.cumsum(x, dim=-1) return torch.flip(x, [-1]) else: return x
[docs] def step(self, inputs, c_last, h_last, interval): x_in = inputs # Integrate inter-visit time intervals interval = interval.unsqueeze(-1) x_out1 = self.kernel(torch.cat((x_in, interval), dim=-1)) x_out2 = self.recurrent_kernel(torch.cat((h_last, interval), dim=-1)) if self.dropconnect: x_out1 = self.nn_dropconnect(x_out1) x_out2 = self.nn_dropconnect_r(x_out2) x_out = x_out1 + x_out2 f_master_gate = self.cumax(x_out[:, :self.levels], 'l2r') f_master_gate = f_master_gate.unsqueeze(2) i_master_gate = self.cumax(x_out[:, self.levels:self.levels*2], 'r2l') i_master_gate = i_master_gate.unsqueeze(2) x_out = x_out[:, self.levels*2:] x_out = x_out.reshape(-1, self.levels*4, self.chunk_size) f_gate = torch.sigmoid(x_out[:, :self.levels]) i_gate = torch.sigmoid(x_out[:, self.levels:self.levels*2]) o_gate = torch.sigmoid(x_out[:, self.levels*2:self.levels*3]) c_in = torch.tanh(x_out[:, self.levels*3:]) c_last = c_last.reshape(-1, self.levels, self.chunk_size) overlap = f_master_gate * i_master_gate c_out = overlap * (f_gate * c_last + i_gate * c_in) + (f_master_gate - overlap) * c_last + (i_master_gate - overlap) * c_in h_out = o_gate * torch.tanh(c_out) c_out = c_out.reshape(-1, self.hidden_dim) h_out = h_out.reshape(-1, self.hidden_dim) out = torch.cat([h_out, f_master_gate[..., 0], i_master_gate[..., 0]], 1) return out, c_out, h_out
[docs] def forward(self, input_data): """ Parameters ---------- input_data = { 'X': shape (batchsize, n_timestep, n_featdim) 'M': shape (batchsize, n_timestep) 'cur_M': shape (batchsize, n_timestep) 'T': shape (batchsize, n_timestep) } Return ---------- all_output, shape (batchsize, n_timestep, n_labels) predict output of each time step cur_output, shape (batchsize, n_labels) predict output of last time step """ X = input_data['X'] M = input_data['M'] cur_M = input_data['cur_M'] T = input_data['T'] batch_size, time_step, feature_dim = X.size() c_out = torch.zeros(batch_size, self.hidden_dim).to(self.device) h_out = torch.zeros(batch_size, self.hidden_dim).to(self.device) tmp_h = torch.zeros_like(h_out, dtype=torch.float32).view(-1).repeat(self.conv_size).view(self.conv_size, batch_size, self.hidden_dim).to(self.device) tmp_dis = torch.zeros((self.conv_size, batch_size)).to(self.device) h = [] origin_h = [] distance = [] for t in range(time_step): out, c_out, h_out = self.step(X[:, t, :], c_out, h_out, T[:, t]) cur_distance = 1 - torch.mean(out[..., self.hidden_dim:self.hidden_dim+self.levels], -1) cur_distance_in = torch.mean(out[..., self.hidden_dim+self.levels:], -1) origin_h.append(out[..., :self.hidden_dim]) tmp_h = torch.cat((tmp_h[1:], out[..., :self.hidden_dim].unsqueeze(0)), 0) tmp_dis = torch.cat((tmp_dis[1:], cur_distance.unsqueeze(0)), 0) distance.append(cur_distance) #Re-weighted convolution operation local_dis = tmp_dis.permute(1, 0) local_dis = torch.cumsum(local_dis, dim=1) local_dis = torch.softmax(local_dis, dim=1) local_h = tmp_h.permute(1, 2, 0) local_h = local_h * local_dis.unsqueeze(1) #Re-calibrate Progression patterns local_theme = torch.mean(local_h, dim=-1) local_theme = self.nn_scale(local_theme) local_theme = torch.relu(local_theme) local_theme = self.nn_rescale(local_theme) local_theme = torch.sigmoid(local_theme) local_h = self.nn_conv(local_h).squeeze(-1) local_h = local_theme * local_h h.append(local_h) origin_h = torch.stack(origin_h).permute(1, 0, 2) rnn_outputs = torch.stack(h).permute(1, 0, 2) if self.dropres > 0.0: origin_h = self.nn_dropres(origin_h) rnn_outputs = rnn_outputs + origin_h rnn_outputs = rnn_outputs.contiguous().view(-1, rnn_outputs.size(-1)) if self.dropout > 0.0: rnn_outputs = self.nn_dropout(rnn_outputs) output = self.nn_output(rnn_outputs) output = output.contiguous().view(batch_size, time_step, self.output_dim) all_output = torch.sigmoid(output) cur_output = (all_output * cur_M.unsqueeze(-1)).sum(dim=1) return all_output, cur_output
[docs]class StageNet(BaseControler): """ StageNet: Stage-Aware Neural Networks for Health Risk Prediction. """ def __init__(self, expmodel_id = 'test.new', n_epoch = 100, n_batchsize = 5, learn_ratio = 1e-4, weight_decay = 1e-4, n_epoch_saved = 1, hidden_size = 384, conv_size = 10, levels = 3, dropconnect = 0.3, dropout = 0.3, dropres = 0.3, batch_first = True, loss_name = 'L1LossSigmoid', target_repl = False, target_repl_coef = 0., aggregate = 'sum', optimizer_name = 'adam', use_gpu = False, gpu_ids = '0' ): """ Applies an Attention-based Bidirectional Recurrent Neural Networks for an healthcare data sequence Parameters ---------- exp_id : str, optional (default='init.test') name of current experiment n_epoch : int, optional (default = 100) number of epochs with the initial learning rate n_batchsize : int, optional (default = 5) batch size for model training learn_ratio : float, optional (default = 1e-4) initial learning rate for adam weight_decay : float, optional (default = 1e-4) weight decay (L2 penalty) n_epoch_saved : int, optional (default = 1) frequency of saving checkpoints at the end of epochs hidden_size : int, optional (default = 384) conv_size : int, optional (default = 10) levels : int, optional (default = 3) dropconnect : int, optional (default = 0.3) dropout : int, optional (default = 0.3) dropres : int, optional (default = 0.3) batch_first : bool, optional (default = False) If True, then the input and output tensors are provided as (batch, seq, feature). loss_name : str, optional (default='SigmoidCELoss') Name or objective function. use_gpu : bool, optional (default=False) If yes, use GPU recources; else use CPU recources gpu_ids : str, optional (default='') If yes, assign concrete used gpu ids such as '0,2,6'; else use '0' """ super(StageNet, self).__init__(expmodel_id) self.n_batchsize = n_batchsize self.n_epoch = n_epoch self.learn_ratio = learn_ratio self.weight_decay = weight_decay self.n_epoch_saved = n_epoch_saved self.hidden_size = hidden_size self.conv_size = conv_size self.levels = levels self.dropconnect = dropconnect self.dropout = dropout self.dropres = dropres self.batch_first = batch_first self.loss_name = loss_name self.target_repl = target_repl self.target_repl_coef = target_repl_coef self.aggregate = aggregate self.optimizer_name = optimizer_name self.use_gpu = use_gpu self.gpu_ids = gpu_ids self._args_check() def _build_model(self): """ Build the crucial components for model training """ if self.is_loadmodel is False: _config = { 'input_dim' : self.input_size, 'hidden_dim' : self.hidden_size, 'conv_size' : self.conv_size, 'levels' : self.levels, 'dropconnect' : self.dropconnect, 'dropout' : self.dropout, 'dropres' : self.dropres, 'label_size' : self.label_size, 'device' : self.device } self.predictor = callPredictor(**_config).to(self.device) self._save_predictor_config({key: value for key, value in _config.items() if key != 'device'}) if self.dataparallal: self.predictor= torch.nn.DataParallel(self.predictor) self.criterion = callLoss(task = self.task_type, loss_name = self.loss_name, target_repl = self.target_repl, target_repl_coef = self.target_repl_coef, aggregate = self.aggregate) self.optimizer = self._get_optimizer(self.optimizer_name)
[docs] def fit(self, train_data, valid_data, assign_task_type = None): """ Parameters ---------- train_data : { 'x':list[episode_file_path], 'y':list[label], 'l':list[seq_len], 'feat_n': n of feature space, 'label_n': n of label space } The input train samples dict. valid_data : { 'x':list[episode_file_path], 'y':list[label], 'l':list[seq_len], 'feat_n': n of feature space, 'label_n': n of label space } The input valid samples dict. assign_task_type: str (default = None) predifine task type to model mapping <feature, label> current support ['binary','multiclass','multilabel','regression'] Returns ------- self : object Fitted estimator. """ self.task_type = assign_task_type self._data_check([train_data, valid_data]) self._build_model() train_reader = self._get_reader(train_data, 'train') valid_reader = self._get_reader(valid_data, 'valid') self._fit_model(train_reader, valid_reader)
[docs] def load_model(self, loaded_epoch = '', config_file_path = '', model_file_path = ''): """ Parameters ---------- loaded_epoch : str, loaded model name we save the model by <epoch_count>.epoch, latest.epoch, best.epoch Returns ------- self : object loaded estimator. """ predictor_config = self._load_predictor_config(config_file_path) predictor_config['device'] = self.device self.predictor = callPredictor(**predictor_config).to(self.device) self._load_model(loaded_epoch, model_file_path)
def _args_check(self): """ Check args whether valid/not and give tips """ assert isinstance(self.n_batchsize,int) and self.n_batchsize>0, \ 'fill in correct n_batchsize (int, >0)' assert isinstance(self.n_epoch,int) and self.n_epoch>0, \ 'fill in correct n_epoch (int, >0)' assert isinstance(self.learn_ratio,float) and self.learn_ratio>0., \ 'fill in correct learn_ratio (float, >0.)' assert isinstance(self.weight_decay,float) and self.weight_decay>=0., \ 'fill in correct weight_decay (float, >=0.)' assert isinstance(self.n_epoch_saved,int) and self.n_epoch_saved>0 and self.n_epoch_saved < self.n_epoch, \ 'fill in correct n_epoch (int, >0 and <{0}).format(self.n_epoch)' assert isinstance(self.hidden_size,int) and self.hidden_size>0, \ 'fill in correct hidden_size (int, 8)' assert isinstance(self.conv_size,int) and self.conv_size>0, \ 'fill in correct conv_size (int, 10)' assert isinstance(self.levels,int) and self.levels>0, \ 'fill in correct levels (int, 10)' assert isinstance(self.dropconnect,float) and self.dropconnect>=0. and self.dropconnect<1., \ 'fill in correct dropconnect (float, >=0 and <1.)' assert isinstance(self.dropout,float) and self.dropout>=0. and self.dropout<1., \ 'fill in correct dropout (float, >=0 and <1.)' assert isinstance(self.dropres,float) and self.dropres>=0. and self.dropres<1., \ 'fill in correct dropres (float, >=0 and <1.)' assert isinstance(self.batch_first,bool), \ 'fill in correct batch_first (bool)' assert isinstance(self.target_repl,bool), \ 'fill in correct target_repl (bool)' assert isinstance(self.target_repl_coef,float) and self.target_repl_coef>=0. and self.target_repl_coef<=1., \ 'fill in correct target_repl_coef (float, >=0 and <=1.)' assert isinstance(self.aggregate,str) and self.aggregate in ['sum','avg'], \ 'fill in correct aggregate (str, [\'sum\',\'avg\'])' assert isinstance(self.optimizer_name,str) and self.optimizer_name in ['adam'], \ 'fill in correct optimizer_name (str, [\'adam\'])' assert isinstance(self.use_gpu,bool), \ 'fill in correct use_gpu (bool)' assert isinstance(self.loss_name,str), \ 'fill in correct optimizer_name (str)' assert isinstance(self.gpu_ids,str), \ 'fill in correct use_gpu (str, \'0,2,7\')' self.device = self._get_device()